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Testosterone Dosage


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#1 jjstrummer

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Posted 22 October 2011 - 06:55 AM

Hi all -

I just started testosterone about a week and a half ago and I am very, very happy to be moving forward. I went to a clinic that has experience with FTMs, but as I was looking over my prescription bottle last night, I started to wonder if I had been given the appropriate dosage. I have had two shots thus far. 1 mL of 200 mg/mL testosterone cypionate per WEEK. So, that means I am getting 200mg a week doesn't it? Isn't that a lot - especially to start out with?

Has anyone else out there been given this high a dose? The instructions on the bottle and that I was given at the clinic was definitely a shot of 1 mL per week - not bi-weekly. If this is too high, I can always cut back to 1 mL every two weeks or .5 mL a week. What would the difference be in terms of how I would likely feel? Are weekly shots better to keep the levels more even?

Just looking for some feedback. Thanks!

JJ

#2 misha

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Posted 22 October 2011 - 07:19 PM

That is an unusually high dosage, even if you still have your ovaries. It is usually half or a quarter of this amount.

#3 Christian_transman

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Posted 22 October 2011 - 09:47 PM

Yeah, seems like you should be starting out slower, and taking that dose maybe once every 10 days or 2 weeks, not every week.

#4 juniperblue

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Posted 22 October 2011 - 09:59 PM

Hey JJ,

I don't know much about T but when in doubt, it might be wise to lower the amount. The lower dose will not cause harm but a higher dose that you are not ready for could be dangerous.

Get a second opinion from a reputable Endocrinologist as soon as possible.

Best to You,

- J

#5 Thomas

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Posted 24 October 2011 - 06:38 AM

Hey, JJ!

I'm on 1/2 mL every two weeks, which is, from what I understand, a fairly common dosage level. So yes, your dosage level does sound like it's higher than the norm.

That doesn't mean it's the wrong dosage necessarily. If the clinic did bloodwork for you before they prescribed your hormones, they may have seen that your pre-existing tesosterone levels were lower than average, for example. You should go to the clinic and ask why you were prescribed the dosage that you were. If they don't give you a satisfactory answer, then definitely see if you can do as juniperblue suggested and seek a second opinion.

Also, weekly shots are often preferred over bimonthly shots because of the exact reason you cited--to help keep hormone levels even. But in such cases, the bimonthly dosage is simply halfed. So, if I were to take a weekly shot, I would take 1/4 mL every week, instead of 1/2 mL every two weeks.

Good luck!

~Thom

#6 jjstrummer

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Posted 24 October 2011 - 10:16 AM

Hey -

Thanks guys for weighing in. I just talked with the clinic and they assure me this is the normal dose they prescribe for FTMs. But I have done a lot of research on the Internet over the past few days and can't find a dose this high listed anywhere as normal. I feel fine, but I don't want to do any injury to myself on a blood cell/liver enzyme level. I am trying to find someone to give me a second opinion, but I had a hard enough time finding this clinic to begin with. I am thinking about just halving the dose on my own. I have a follow-up appointment in about 4 weeks for bloodwork, so it will become clear then where my levels are and if the dosage is too much/just right.

Sigh. I wish it was easier to find information out there - there just haven't been enough studies done on this issue. And I hate that it is so difficult to find knowledgeable, experienced health care providers.

Anyway, thanks again for the input!
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#7 TranZwear

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Posted 24 October 2011 - 12:21 PM

That dosage is for every two weeks, not weekly. Then maybe it will be for every 10 days, but definitely not every week, that is twice as much as you should start with.
Question your MD...
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#8 TranZwear

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Posted 24 October 2011 - 12:31 PM

You sure it wasn't 100mg instead of 1 ML? Because 100 mg would make sense. Your first labs won't show much results as far as what your T levels are. You are definitely on twice as much as most people start out on, even continue on. This can be detrimental to your health and even tho they say this is the "normal" dosage they use, it may not be what is recommended. CHeck out these two documents written by MD;s who work in the trans field.
http://www.nickgorton.org/..
click at the bottom of the page for the document in Office. Also http://www.ftmguide....tandhealth.html and
http://transhealth.v...ormones-FTM.pdf
Recommended testosterones and their dosages:


testosterone esters (transdermal, enanthate, Sustanon, cypionate)
200-250 mg/2 weeks intramuscular injection [1]
250-400 mg/2-3 weeks intramuscular injection [2]
Androgen treatment has an unfavorable effect on the lipid profile. Oral androgens such as mesterolone and fluoxymesterone are too weak for the induction of virilization.
Good luck

#9 jjstrummer

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Posted 24 October 2011 - 03:42 PM

Yes - I am sure that what he prescribed was 200 mg per week. I confirmed that with him today - when I was questioning whether or not that was REALLY the dosage he felt was appropriate. The bottle is 200mg/mL and he verified that the dosage is 1 mL per week for a total of 200 mg of testosterone a week. He seemed to think this was perfectly fine and normal and that is what he prescribes for all FTMs. I'm not sure he knows what he is doing. I think I am going to cut it back to 0.5 mL a week - for a dosage of 100 mg per week. I feel more comfortable with that dosage. I have an appointment in 4 weeks and can see what my testosterone levels are then and make sure the rest of my bloodwork is OK. Hopefully that will work out.

Thanks to everyone who has shared their thoughts and opinions on this! You have all backed up what I found in my own research.

#10 Thomas

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Posted 25 October 2011 - 11:44 AM

Cool. Let us know how things continue to go (if you want to share with us, of course).

As juniperblue said, a too-low dosage shouldn't harm you, though a too-high one could. Really, the main concern with a too-low dosage is that you won't see the physical masculinization that you'd like. That happened with me. I started very conservatively--because I wanted to do so, not because my doctor made me--and my doctor ended up increasing my dosage as time went on.

#11 Always Jim

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Posted 25 October 2011 - 07:52 PM

I use a cream so I don't know how that translates. I apply .05 ML of 100MG/GM every day. I started out at 1ML but after about 2 weeks I discovered it was converting to estrogen so cut back to .05ML. We plan to start increasing the dosage slowly as my body gets used to it.

#12 juniperblue

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Posted 25 October 2011 - 09:13 PM

Always Jim,

What does your endocrinologist think about natural Aromatase inhibitors like Indol 3 Carbinol ( from Broccoli and other cruciferous veggies) , Chrysin ( from Passion Flower) and Camomile? People with high levels of Aromatase will convert excess T to Estrogen. Body builders have used aromatse inhibitors for years and I use them to reduce my risk of estrogenic cancers ( crappy genetics) . I wrote a little more about this on the Health and Fitness Topic under Natural T boosters and Estrogen Reducers.

Good Luck,

- J

#13 Always Jim

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Posted 29 October 2011 - 05:57 AM

I haven't even thought much about Aromatase inhibitors since I read that they were only really necessary for those who still had ovaries. My research indicated that .025 to .05 ML is the typical starting dosage for people who have had a complete hysterectomy. Which I had 15 years ago.

#14 misha

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Posted 31 October 2011 - 09:13 AM

Its the male body builders who use aromatase inhibitors because at the end of their doping /staking cycle all that extra T aromatizes and they get breasts, which they use aromatase inhibitors to prevent since they do not have ovaries. Female body builders who have ovaries and stack have no need for aromatase inhibitors, although they suffer from permanent masculinization. Most femal body builders who are using anabolics get hair waeaves, electrolysis, and sound hoarse for life. The unfortunate thing for them is they want to appear ripped like their male counter parts but still need to look like women. Only natal men and women with estrogenic cancers need aromatase inhibitors (unless they transition befor they are old enough for testosterone). Real aromatase inhibitors are very dangerous. They are considered chemotheraputic agents and have never been given to a cancer survivor longer than 5 years.

#15 juniperblue

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Posted 31 October 2011 - 12:02 PM

Thanks for the extra medical information Misha. My last Doctor didn't go into great detail when she made the suggestion for Indole 3 Carbinol ... it is frustrating how short Doctor's visits are .. there really is little time to discuss these things in depth. The old Doctor was also a Acupuncturist and so, some of her suggestions were more on the Eastern Medicine side. I now have a new Doctor who knows nothing about herbal medicine.

I am not sure if the natural supplements will be strong enough to help someone taking T. It sounds like they may not be and that they may not be appropriate for most transmen (anyway.).

I am not taking a high enough amount (of any of the three) that I mentioned to feel a concern for negative side effects. I can't really tell if they are doing much but I am hoping that at least the Indole 3 Carbinol is binding excess estrogen. I have a library of herbal books but they are limited in what they say ... probably for liability reasons.

The Chrysin I take every other day and the Chamomile I take on the days that I don't take Chrysin. They are both mildly calming so I take them late at night. It is frustrating that there are few medical studies on over-the-counter herbs. Because there is so little solid information, I take herbal remedies with caution and I always advise others to ask their Doctors first before trying anything. I guess a Naturopath would be the way to go but I can't afford another private Doctor and I don't know of a good one anyway. Sigh.

- J

#16 jean

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Posted 10 November 2011 - 09:49 AM

hello guy's
i have used hormones sinds 1981. when i started, i also get a high doses, 3 times higher then others i knew. for years i was very happy with that. but in 2003 i have had a heartattack. in november 2011 i got a new one, so now i am asking myself, did i not got to much?
so, please, be carefull
greetongs jean from holland

#17 jjstrummer

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Posted 08 December 2011 - 07:47 PM

Hello again everyone -

After my original post, I dropped my dosage down to 100 mg a week - half of what I was prescribed when I began testosterone on 10/12/11. After four weeks at 100 mg, I went in for a blood test to see where my levels were. I was close to the end of my dosing cycle - just 2 days from my next shot. My T level was 1428. Pretty high. I am dropping back to about 65 mg a week now and will have my blood tested again in another 4 weeks. I'm certainly glad I had cut the original dosage in half! Otherwise, I might be turning green and ripping everything but some purple boxers off...

I know that short term the high levels won't hurt me, but I certainly want to get everything dialed in for the right dosage to achieve normal, healthy, stable levels. The good thing is that I have been feeling really good. I didn't have any bad side effects or anything. All jokes about the Hulk aside, I haven't even had any real mood swings or anything like that. I generally feel strong, healthy and calm. All my other bloodwork was normal.

I have to say though that I don't really feel like I am getting great medical care. I feel like I know more than my practitioner. I also feel in general that there isn't a lot of good information out there. When I try to research issues related to testosterone for FTMs, there is such scattershot info that I feel like there is no good, reliable source to turn to. A lot of that is because no one seems to really be researching and compiling that information. To some degree, I feel like we are guinea pigs.

I guess I am throwing this out there and sharing my info because I think it could be a really helpful thing for us to share the knowledge and experience we have with testosterone dosage with one another. I know that everyone's body and biochemistry is different. Different dosages are going to affect different people in different ways. I get that. But maybe if we share all the specific information we have with one another, we can start to build a body of empirical data that may be helpful in some way. Just an idea. Born out of frustration with finding the information I was looking for to help me figure out what to do when my medical provider seemed clueless.

Thanks again to everyone who posted and shared their thoughts about my situation. Hope you all have very happy holidays!!

JJ

#18 juniperblue

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Posted 08 December 2011 - 10:07 PM

Hey JJ,

Great to hear that you were intuitive and listened to your body on this one. I have been managing a rare endocrine disorder and my medical care has been pretty crappy because so few Doctors have any experience with my condition. I have limited financial resources to pay out of pocket for specialists and I am often shocked by how little the Doctor's seem to know. From this I have learned that it is always good to be vigilant. Do do all that you can to be as well informed as possible. Write all of your questions out before your appointment and share research that you find if it seems relevant and from a reputable medical journal or other credible publication. Consider taking an ally in with you when you see your Doctor as well. it is good to have someone there to take notes. In my experience, my care is often better when I have an ally with me.

Thanks for starting this post .. It may help a lot of guys, especially those who are just getting started on T.

Best to You,

- J




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